Go Luxury Villas - Vacation Rentals in Depew

Quiet suburban home 10 minutes from airport/25 min from Niagara Falls From US $184
         

10.0 (16 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo From US $363
         

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10.0 (1 Review)
House
  • Parking
  • Pet Friendly
  • Balcony/Terrace
Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo From US $427
         

KING Master En-Suite- BRAND NEW Home- Buffalo's Best Kept Secret! From US $307
         

Work or Play this is your Home Away From US $151
         

10.0 (54 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • TV
Spacious/Comfy/Private Home near Buffalo/Bills/Airport/Niagara Falls From US $659
         

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo From US $339
         

10.0 (29 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Luxury Places to Stay in Depew

Over 161+ Luxury Places to Stay in or Near Depew
King bed fenced backyard and parking From US $595
         

9.4 (3 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Perfect Vacation Cozy Lancaster Village Bungalow From US $515
         

Fireman's Park Quarters From US $499
         

9.2 (5 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Top-Rated Vacation Rentals with a Pool in Depew

Over 39+ Top-Rated Vacation Rentals with a Pool in or Near Depew
Hilton Garden Inn Buffalo Airport From US $173
         

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9.0 (1013 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Courtyard Buffalo Airport From US $154
         

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9.0 (1003 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Springhill Suites Buffalo Airport From US $249
         

9.0 (879 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
TownePlace Suites Buffalo Airport From US $265
         

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9.0 (820 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Tru by Hilton Williamsville Buffalo Airport From US $158
         

8.8 (1004 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Home2 Suites by Hilton Williamsville Buffalo Airport From US $238
         

Home2 Suites By Hilton Williamsville Buffalo Airport From US $238
         

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8.8 (106 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Hilton Garden Inn Buffalo Airport From US $188
         

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8.7 (197 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly

Pet-Friendly Vacation Rentals in Depew

Over 60+ Pet-Friendly Vacation Rentals in or Near Depew
Dog-Friendly Home ~ 14 Mi to Highmark Stadium From US $279
         

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9.7 (4 Reviews)
House
  • Parking
  • Pet Friendly
  • Security/Safety
La Quinta Inn by Wyndham Buffalo Airport From US $117
         

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8.0 (1603 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Buffalo, NY 3 bedroom village home by carol From US $410
         

10.0 (2 Reviews)
Cottage
  • Air Conditioner
  • Parking
  • Pet Friendly
Charming 2-bedroom apartment near airport in peaceful Cheektowaga From US $204
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Modern Home 3 Minutes from Airport! From US $308
         

10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Buffalo Ny Carols Cape From US $352
         

9.8 (7 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Wonderful 3-bedroom house in Cheektowaga From US $187
         

8.4 (6 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
See More Pet-Friendly Vacation Rentals in Depew on PetFriendly.io

Large Vacation Homes & Villas in Depew

Over 7+ Large Vacation Homes & Villas in or Near Depew
Sweet home, King bed, backyard and parking From US $428
         

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9.0 (15 Reviews)
House
  • Parking
  • Pet Friendly
  • Security/Safety
Luxury Villa From US $173
         

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8.9 (26 Reviews)
Villa
  • Air Conditioner
  • Parking
  • Security/Safety
2UNITModernFarmhouse Sleeps13 From US $388
         

8.8 (11 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Fully renovated house in Bowmansville/Depew From US $230
         

Wheelchair Accessible Vacation Homes in Depew

Over 40+ Wheelchair Accessible Vacation Homes in or Near Depew
Courtyard by Marriott Buffalo Airport From US $242
         

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8.6 (213 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Salvatores Grand Hotel From US $192
         

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9.6 (1002 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
The Delavan Hotel From US $171
         

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8.5 (398 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
The Delavan Hotel & Spa From US $180
         

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9.0 (1005 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
Aloft by Marriott Buffalo Airport From US $143
         

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8.5 (224 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Best Western Buffalo Inn & Suites From US $104
         

8.8 (892 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Wheelchair Accessible

Depew Vacation Rentals and Airbnb Places to Stay Under $200

Over 83+ Depew Vacation Rentals and Airbnb Places to Stay Under $200
Home away from home with private yard From US $110
         

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10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • View
Fairfield Inn & Suites by Marriott Buffalo Airport From US $168
         

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8.6 (1003 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Luxury Villan From US $178
         

9.8 (15 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Private Apartment next to Airport! From US $161
         

9.6 (13 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Renovated | Near Airport | Central Location From US $146
         

9.0 (24 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Safe Large Parking Quiet Laundry AC BBQ Patio From US $196
         

New
Apartment
  • Air Conditioner
  • Pet Friendly
  • Security/Safety
Lovely cozy 3-bedroom ranch house/near airport From US $188
         

10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Instantly Bookable Vacation Homes in Depew

Over 37+ Instantly Bookable Vacation Homes in or Near Depew
*Perfect Vacation* Cozy Lancaster Village Bungalow From US $317
         

Buffalo Airport Retreat: Spacious-Relaxing-Parking From US $210
         

10.0 (1 Review)
House
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens
BUF Airport Ranch 3BR1.5B Cheektowaga NY/Sleeps 8 From US $397
         

Large Yard | Deck | 20 Min to Highmark Stadium From US $334
         

3-bedroom house in close to the airport Buffalo family- friendly no pets allowed From US $304
         

3-bedroom house in delightful Cheektowaga with cool AC From US $262
         

New
House
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens

About Depew Vacation Rentals

With more than 170 Depew vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Goluxuryvillas and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at a rental property in Depew.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With Goluxuryvillas Depew, you have the flexibility of comparing different options of various deals with a single click. Looking for a rental by owner with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner, and other popular Airbnb-style properties in Depew. Places to stay near Depew are 442.51 ft² on average, with prices averaging US $227 a night.

Goluxuryvillas makes it easy and safe to find and compare vacation rentals in Depew with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Top Rental Accommodation Types in Depew

Type Count
Vacation Homes 79
Hotels 62
Holiday Apartments 26
Cottages 2
Villas 1

Use these Quick Filters to Find a Vacation Rental in Depew

Pro Tip: Goluxuryvillas makes it easy to compare the best listings on Goluxuryvillas homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Goluxuryvillas homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Depew.

Weather in Depew

View the weather forecast for Depew before booking your Depew Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Depew Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Depew?
How many vacation rentals are available in Depew?

Currently, the total number of properties listed in 2026 is over 170 in the Depew area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Depew.